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DeCS
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Descriptor English:
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2',5'-Oligoadenylate Synthetase
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Descriptor Spanish:
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2',5'-Oligoadenilato Sintetasa
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Descriptor Portuguese:
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2',5'-Oligoadenilato Sintetase
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Synonyms English:
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2',5'-Oligoadenylate Polymerase
2-5A Synthetase
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Tree Number:
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D08.811.913.696.445.625
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Definition English:
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An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions. EC 2.7.7.-. |
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History Note English:
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83
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Allowable Qualifiers English:
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Record Number:
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21042
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Unique Identifier:
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D015088
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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